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apalutamide will lower the level or impact of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Coadministration of apalutamide, a strong CYP3A4 inducer, with medication which can be CYP3A4 substrates can lead to lower publicity to those drugs.Drug interactions may well change how your drugs w